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Metabolism Alprazolam is extensively metabolized in human beings, mostly by cytochrome P450 3A4 (CYP3A4), to two major Lively metabolites while in the plasma: four-hydroxyalprazolam and α-hydroxyalprazolam. The plasma circulation amounts of The 2 Lively metabolites are fewer than four% with the dad or mum. The claimed relative potencies in benzodi